The Minnesota Vikings went back to the medical tent after running into their own blockade and stumbling.
He ruled him out for the rest of the close game against the Detroit Lions with a shoulder injury.
Although the severity of the injury is unclear, Cook has lost time during his NFL career. The three-time pro bowler has never played more than 14 games in a season.
Dalvin Cook's day ended early and fans are feeling the deja vu when the star hurt his back.
After covering a total of 36 yards in Monday night's loss to the Philadelphia Eagles, Cook compiled 96 rushing yards and one touchdown before leaving Sunday's game early.
His common sense, Alexander Matison, scored a touchdown in the fourth quarter. The ensuing extra score narrowed the deficit to 24-21.
As fantasy manager Waver ran to The Wire to check on Mattison's availability, Vikings fans would be hoping that Cook could return against the New Orleans Saints in London.